FISIOLOGIA EM GERAL
(General physiology)
ARTIGOS
Bardgard AJ, 1997 Functional characterisation of Eskimo dog hemoglobin: II. The interplay of HCO(3)- and Cl-. Comp Biochem Physiol A Physiol 117(3), 375-381 (1997)
Bardgard AJ, 1997 Functional characterisation of Eskimo dog hemoglobin: I. Interaction of Cl- and 2,3-DPG and its importance to oxygen unloading at low temperature. Comp Biochem Physiol A Physiol 117(3), 367-373 (1997)
Drag MD, 1991 Hematologic values of captive Mexican wolves. Am J Vet Res 52(11), 1891-1892 (1991)
DelGiudice GD, 1991 Gray wolf density and its association with weights and hematology of pups from 1970 to 1988. J Wildl Dis 27(4), 630-636 (1991)
Kreeger TJ, 1991 Diazepam-induced feeding in captive gray wolves (Canis lupus). Pharmacol Biochem Behav 39(3), 559-561 (1991)
Kreeger TJ, 1990 Physiological and behavioral responses of gray wolves (Canis lupus) to immobilization with tiletamine and zolazepam. J Wildl Dis 26(1), 90-94 (1990)
Kreeger TJ, 1989 Physiological response of gray wolves to butorphanol-xylazine immobilization and antagonism by naloxone and yohimbine. J Wildl Dis 25(1), 89-94 (1989)
Kreeger TJ, 1988 Use of xylazine sedation with yohimbine antagonism in captive gray wolves. J Wildl Dis 24(4), 688-690 (1988)
Kreeger TJ, 1987 Cardiovascular and behavioral responses of gray wolves to ketamine-xylazine immobilization and antagonism by yohimbine. J Wildl Dis 23(3), 463-470 (1987)
McCue PM, 1987 Hematologic values of the endangered San Joaquin kit fox, Vulpes macrotis mutica. J Wildl Dis 23(1), 144-151 (1987)
Pospisil J, 1987 Basic haematological values in carnivores--I. The Canidae, the Hyaenidae and the Ursidae. Comp Biochem Physiol A 86(4), 649-652 (1987)
Morley JE, 1986 The effect of peripheral administration of peptides on food intake, glucose and insulin in wolf pups. Peptides 7(6), 969-972 (1986)
Shultz TD, 1974 Influence of dietary fatty acids on the composition of plasma fatty acids in the tundra wolf (Canis lupus tundrarum). Comp Biochem Physiol A 49(3A), 575-581 (1974)
Wideback K. Seal US. Kronvall G. Receptor in group C and G streptococci detects albumin structures present in mammalian species. Infection & Immunity. 36(2):469-75, 1982 May. Abstract The presence of albumin structures with the capacity to bind to a surface receptor in group C and G streptococci was studied in serum samples from 45 mammalian species representing 15 different orders, using an inhibition assay. The ability of animal sera to inhibit the uptake of radiolabeled human serum albumin by the streptococci indicated the presence of such albumin structures. Positive reactions were found in species of most orders tested, with Marsupialia as a notable exception. All Carnivora sera tested were strongly positive. In some orders such as Artiodactyla both positive and negative species were identified. Serum samples from 62 bird species representing 15 orders and from 5 fish species were also tested in the inhibition assay. None of these serum samples was capable of inhibiting the uptake of human serum albumin by streptococci. Some differences were also noted in the results obtained with group C and G streptococci from human and bovine sources, respectively, indicating the presence of two types of receptors. The present studies suggest a phylogenetic origin of albumin structures with affinity for the streptococcal receptor to a period after the divergence of Marsupialia from the other mammalian orders.
Smith GJ. Rongstad OJ. Serologic and hematologic values of wild coyotes in Wisconsin. Journal of Wildlife Diseases. 16(4):491-7, 1980 Oct. Abstract Blood samples were obtained from 30 coyotes (Canis latrans) captured in northern Wisconsin in conjunction with radio-telemetry studies. Samples were assayed for seven hematologic values, seven serum chemistries, serum albumin, globulin and total protein. Results are given with respect to sex and age and are compared with available data for captive wild and pen-raised coyotes. Leukocyte counts were greater for males than females and packed cell volumes were greater for adults than young, possibly due to differential response to capture and handling stress. Hemoglobin concentrations and calcium levels suggest differences in nutrition between pen-raised and wild coyotes. Sex and age differences in serum calcium for wild coyotes probably reflect nutritional differences between groups examined. Juvenile coyote serum alkaline phosphatase levels declined curvilinearly with age for coyotes less than one year old, suggesting a possible technique for separating juveniles and yearlings captured in autumn that are released for research purposes. Elevated glucose levels and leukocyte counts in wild coyotes may reflect greater handling stress than for pen-raised and captive coyotes. No significant sex or age effects were found for levels of serum urea nitrogen, total protein, cholesterol, and total bilirubin.
Schmitt J. Durr UM. [The differentiation of animal proteins using vertical polyacrylamid gel electrophoresis. 4. Serum proteins of the Carnivora]. [German] Deutsche Tierarztliche Wochenschrift. 77(22):584-7, 1970 Nov 15.
Burr JR, 1997 Serum biochemical values in sled dogs before and after competing in long-distance races. J Am Vet Med Assoc 211(2), 175-179 (1997)
Hinchcliff KW, 1996 Performance failure in Alaskan sled dogs: biochemical correlates. Res Vet Sci 61(3), 271-272 (1996)
Goubran Botros H, 1996 Cross-antigenicity of horse serum albumin with dog and cat albumins: study of three short peptides with significant inhibitory activity towards specific human IgE and IgG antibodies. Immunology 88(3), 340-347 (1996)
Yuan H, 1996 Release of CuPTSM from human serum albumin after addition of fatty acids. J Inorg Biochem 61(4), 251-259 (1996)
Miller MJ, 1994 Plasma proteins as early biomarkers of exposure to carcinogenic aromatic amines. Chem Biol Interact 93(3), 221-234 (1994)
Masuoka J, 1994 Zinc(II) and copper(II) binding to serum albumin. A comparative study of dog, bovine, and human albumin. J Biol Chem 269(41), 25557-25561 (1994)
McClelland G, 1994 Increased capacity for circulatory fatty acid transport in a highly aerobic mammal. Am J Physiol 266(4), R1280-R1286 (1994)
Spitzauer S, 1994 Molecular characterization of dog albumin as a cross-reactive allergen. J Allergy Clin Immunol 93(3), 614-627 (1994)
Miller I, 1993 Peculiarities in electrophoretic behavior of different serum albumins. Electrophoresis 14(12), 1312-1317 (1993)
Montaser A, 1992 Comparison of copper binding components in dog serum with those in other species. Proc Soc Exp Biol Med 200(3), 321-329 (1992)
Andersson L, 1991 Immobilized metal ion affinity chromatography of serum albumins. Bioseparation 2(1), 15-22 (1991)
McArdle HJ, 1990 Role of albumin's copper binding site in copper uptake by mouse hepatocytes. Am J Physiol 258(6), G988-G991 (1990)
Pilati CF, 1990 Macromolecular transport in canine coronary microvasculature. Am J Physiol 258(3), H748-H753 (1990)
Robertson A, 1990 Comparison of the binding characteristics of serum albumins from various animal species. Dev Pharmacol Ther 15(2), 106-111 (1990)
Reed RK, 1989 Estimation of capillary reflection coefficients and unique PS products in dog paw. Am J Physiol 257(3), H1037-H1041 (1989)
Sanabria P, 1988 Effect of albumin on the width of water channels in venous endothelium. Am J Physiol 255(3), H638-H645 (1988)
Evans GO, 1988 A comparison of two dye-binding methods for the determination of dog, rat and human plasma albumins. J Comp Pathol 98(4), 453-460 (1988)
Jansen B, 1987 Samoyed hereditary glomerulopathy: serial, clinical and laboratory (urine, serum biochemistry and hematology) studies. Can J Vet Res 51(3), 387-393 (1987)
Decock-Le Reverend B, 1987 Isolation and two-dimensional 1H-NMR of peptide [1-24] of dog serum albumin and studies of its complexation with copper and nickel by NMR and CD spectroscopy. Biochim Biophys Acta 912(1), 16-27 (1987)
Manillier C, 1986 ATP turnover and renal response of dog tubules to pH changes in vitro. Am J Physiol 251(5), F919-F932 (1986)
Kusachi S, 1986 Dog coronary artery adenosine receptor: structure of the N6-aryl subregion. J Med Chem 29(6), 989-996 (1986)
Frenette G, 1986 Proteolytic activity of arginine esterase from dog seminal plasma towards actin and other structural proteins. Comparison with trypsin and kallikrein. Int J Biochem 18(8), 697-703 (1986)
Patterson R, 1985 Canine antibodies against formaldehyde-dog serum albumin conjugates: induction, measurement, and specificity. J Lab Clin Med 106(1), 93-100 (1985)
Quon CY, 1985 Biochemical properties of blood esmolol esterase. Drug Metab Dispos 13(4), 420-424 (1985)
Mohanakrishnan P, 1985 Chloride ion nuclear magnetic resonance spectroscopy probe studies of copper and nickel binding to serum albumins. J Pharm Sci 74(1), 61-63 (1985)
Muller D, 1984 Studies of copper(II) binding to glycylglycyl-L-tyrosine-N-methyl amide, a peptide mimicking the NH2-terminal copper(II)-binding site of dog serum albumin by analytical potentiometry, spectrophotometry, CD, and NMR spectroscopy. J Inorg Biochem 21(3), 215-226 (1984)
Glennon JD, 1983 Nickel(II) binding to glycylglycyl-L-tyrosine-N-methyl amide, a peptide mimicking the NH2-terminal nickel(II)-binding site of dog serum albumin: a 1H- and 13C-nuclear magnetic resonance investigation. J Inorg Biochem 19(4), 281-289 (1983)
Glennon JD, 1982 The non-specificity of dog serum albumin and the N-terminal model peptide glycylglycyl-L-tyrosine N-methylamide for nickel is due to the lack of histidine in the third position. Biochem J 203(1), 25-31 (1982)
Wood JG, 1982 Measurement of canine gastric vascular permeability to plasma proteins in the normal and protein-losing states. Gastroenterology 82(4), 725-733 (1982)
Krakowka S, 1981 Quantitative determination of serum origin cerebrospinal fluid proteins in the dog. Am J Vet Res 42(11), 1975-1977 (1981)
Rakhit G, 1981 Electron spin resonance study of the copper(II) complexes of human and dog serum albumins abd some peptide analogs. J Inorg Biochem 15(3), 233-241 (1981)
Giroux E, 1981 Copper and zinc ion binding by bovine, dog, and rat serum albumins. J Inorg Biochem 14(4), 359-362 (1981)
Cianciaruso B, 1981 Histidine, an essential amino acid for adult dogs. J Nutr 111(6), 1074-1084 (1981)
Gabel JC, 1980 Errors in calculated oncotic pressure of dog plasma. Am J Physiol 239(6), H810-H812 (1980)
Bell DR, 1980 Exclusion of plasma proteins in interstitium of tissues from the dog hind paw. Am J Physiol 239(4), H532-H538 (1980)
Eyre DR, 1980 Biosynthesis of collagen and other matrix proteins by articular cartilage in experimental osteoarthrosis. Biochem J 188(3), 823-837 (1980)
Serebriakova LI, 1980 Determination of the diffusion capacity of dog heart capillaries by the double indicator method Biull Eksp Biol Med 89(5), 518-519 (1980)
Jun HW, 1980 Distribution of tetracycline in red blood cells. J Pharm Sci 69(4), 455-457 (1980)
Nechay BR, 1980 Inhibition of adenosine triphosphatases by gold. Arthritis Rheum 23(4), 464-470 (1980)
Fex G, 1980 Subunit exchange between human and dog prealbumins. Scand J Clin Lab Invest 40(1), 71-78 (1980)
Baverel G, 1980 Glutamine metabolism in isolated dog kidney tubules: inhibition by dialysed albumin preparation. J Physiol (Paris) 76(2), 129-132 (1980)
Skrede S, 1979 Fatty acid metabolism during hypothermic perfusion of the isolated dog kidney. Scand J Clin Lab Invest 39(8), 765-771 (1979)
Baverel G, 1978 Lactate and pyruvate metabolism in isolated renal tubules of normal dogs. Kidney Int 14(6), 567-575 (1978)
Nechay BR, 1978 Inhibition by vanadium of sodium and potassium dependent adenosinetriphosphatase derived from animal and human tissues. J Environ Pathol Toxicol 2(2), 247-262 (1978)
Navar PD, 1977 Relationship between colloid osmotic pressure and plasma protein concentration in the dog. Am J Physiol 233(2), H295-H298 (1977)
Hammel EP, 1977 Metabolic responses to exhaustive exercise in racing sled dogs fed diets containing medium, low, or zero carbohydrate. Am J Clin Nutr 30(3), 409-418 (1977)
Modeer T, 1977 Human saliva kallikrein. Biological properties of saliva kallikrein isolated by use of affinity chromatography. Acta Odontol Scand 35(1), 23-29 (1977)
Litterst CL, 1976 Distribution and disposition of platinum following intravenous administration of cis-diamminedichloroplatinum(II) (NSC 119875) to dogs. Cancer Res 36(7), 2340-2344 (1976)
Hood DM, 1976 Evaluation of radioiodinated human serum albumin in the dog for assessment of hemodynamic function. Am J Vet Res 37(2), 227-228 (1976)
Mates A, 1976 Immune response in dog. 3. Antibody formation in dogs and rabbits to human serum proteins and keyhole limpet haemocyanin. Microbios 17(70), 175-187 (1976)
Hippe E, 1975 Solid-phase cobalamin assay using cobalamin-binding protein from dog stomach. Scand J Clin Lab Invest 35(6), 577-582 (1975)
Berdiev NB, 1975 Dynamics of biochemical indices of dog blood serum at high altitudes and on return to low altitude Kosm Biol Aviakosm Med 9(5), 14-19 (1975)
Metz A, 1975 A comparative study of total protein and albumin in man, monkey, dog and rat employing different analytical methods (author's transl) Z Klin Chem Klin Biochem 13(9), 423-426 (1975)
Debas HT, 1975 Chemicals bathing the oxyntic gland area stimulate acid secretion in dog. Gastroenterology 69(3), 654-659 (1975)
Bruggeman TM, 1975 Plasma proteins in canine gastric lymph. Gastroenterology 68(5), 1204-1210 (1975)
Elford BC, 1975 Interactions between temperature and tonicity on cation transport in dog red cells. J Physiol (Lond) 246(2), 371-395 (1975)
Brotherton J, 1975 The counting and sizing of spermatozoa from ten animal species using a Coulter counter. Andrologia 7(3), 169-185 (1975)
Dixon JW, 1974 Isolation, amino acid sequence and copper(II)-binding properties of peptide (1-24) of dog serum albumin. J Biol Chem 249(18), 5872-5877 (1974)
Dive C, 1974 Origin and nature of the proteins of bile. II. A comparative analysis of serum, hepatic lymph and bile proteins in the dog. Eur J Clin Invest 4(4), 241-246 (1974)
Elford BC, 1974 Temperature dependence of cation permeability of dog red cells. Nature 248(448), 522-524 (1974)
Branco D, 1974 Binding of exogenous noradrenaline by the proteins of dog plasma. Naunyn Schmiedebergs Arch Pharmacol 285(4), 367-373 (1974) (no abstract available)
Davis PJ, 1973 Thyroid hormone binding in dog plasma. Endocrinology 93(6), 1445-1448 (1973)
Dixon JW, 1972 Absence of a specific copper(II) binding site in dog albumin is due to amino acid mutation in position 3. Biochem Biophys Res Commun 48(1), 197-200 (1972) (no abstract available)
Sonksen PH, 1971 Distribution and binding of insulin in the dog hindlimb. Am J Physiol 221(6), 1672-1680 (1971)
Appleton DW, 1971 The absence of specific copper (II)-binding site in dog albumin. A comparative study of human and dog albumins. J Biol Chem 246(16), 5040-5046 (1971)
Ganrot PO, 1970 Concentration of trypsin inhibitors of different molecular size and of albumin and haptoglobin in blood and in lymph of various organs in the dog. Acta Physiol Scand 79(2), 280-286 (1970)
Vieira FL, 1970 The state of water in human and dog red cell membranes. J Gen Physiol 55(4), 451-466 (1970)
Brooks GF, 1970 Kinetics of sodium transfer from blood to brain of the dog. Am J Physiol 218(3), 693-702 (1970)
Bruenger FW, 1967 Half-periods of serum proteins in the dog. Am J Vet Res 28(127), 1699-1703 (1967)
Lauer BH, 1969 Wolf milk. I. Arctic wolf (Canis lupus arctos) and husky milk: gross composition and fatty acid constitution. Can J Zool 47(1), 99-102 (1969)
Juneja R K. Christensen K. Andresen E. Gahne B . Frequencies of transferrin types in various breeds of domestic dogs. Animal Blood Groups & Biochemical Genetics 12 (2). 1981. 79-88.0. Abstract Plasma transferrin (Tf) types in dogs were studied by a method of horizontal polyacrylamide gel electrophoresis with a 10% separation gel and a discontinuous buffer system (Tris-citrate-borate, pH 9.0). Samples were analyzed from 1127 dogs belonging to 60 different breeds. TfB and TfC alleles, each in considerably high frequency, were observed in most of the breeds. TfA with relative lower frequency was observed in beagle, cocker spaniel, Doberman pinscher, German shepherd, German shorthaired pointer, Old Danish pointer and poodle. Two rare Tf alleles, TfD and the other designated as TfE, were observed only in cocker spaniel and in poodle, respectively. Basenji (44 samples) and small Muensterlaender (17 samples) showed the highest frequency (0.97) for TfC allele while Carelian bear dog (19 samples) showed the highest frequency (0.97) for TfB allele. In the total material, the frequencies of Tf alleles A, B, C, D and E were 0.0182, 0.5075, 0.4716, 0.0009 and 0.0018, respectively. By using the observed and expected numbers of Tf heterozygotes, the average inbreeding coefficient (F) within breeds was estimated to be 0.14. Six samples of wolf (Canis lupus L.) studied seemed to be of Tf B type. Apparently, some of the plasma proteins and enzymes (albumin, transferrin, eserine resistant esterase), exhibit considerably more polymorphism than that reported for Hb and some of the red cell and tissue enzymes in the domestic dog.
Kakela, R.; Hyvarinen, H. Site-specific fatty acid composition in adipose tissues of several northern aquatic and terrestrial mammals. Comp. Biochem. Physiol. B: Biochem. Mol. Biol., 115B(4), 501-514, 1996
TESES
Waggoner, l Paul. OLFACTORY SENSITIVITY OF THE DOG (CANIS LUPUS FAMILIARIS) TO THE VAPOR FROM COCAINE HYDROCHLORIDE AND METHYL BENZOATE (CANINE DETECTION, FORENSICS). Dissertation Abstracts International. Volume: 58-03, Section: B, page: 1515. Abstract Although dogs are used for a variety of olfactory detection tasks, characteristics of their olfactory detection capabilities for targeted substances have rarely been quantified. The dog-handler team is widely deployed by law enforcement organizations for the detection of illicit drugs such as cocaine hydrochloride (HCL). The following project sought to investigate the olfactory detection characteristics of the dog for vapor emitted from cocaine HCl. The abundance of cocaine HCl in the vapor from cocaine is very low, therefore dogs trained to detect cocaine probably do so on the basis of some other constituent(s) in the vapor from cocaine. Methyl benzoate has been reported to be a consistent and abundant constituent in the vapor from cocaine HCl. Because of its abundance and reports that samples of cocaine smell like methyl benzoate, it has been presumed that methyl benzoate is the constituent of cocaine vapor that controls the detection responses of dogs trained to detect cocaine. The abundance of methyl benzoate has been shown to be dependent on the humidity of the air in which the cocaine is present. Thirteen random source dogs were used in the following five studies: (1) Determination of sensitivity to vapor from (a) pharmaceutical cocaine HCl and (b) illicit cocaine HCl generated under low humidity conditions; (2) determination of sensitivity to vapor from methyl benzoate; (3) investigation of the potential role of methyl benzoate in the detection of vapor from cocaine HCl generated under low humidity conditions; (4) determination of sensitivity to vapor from illicit cocaine HCl generated under high humidity conditions; (5) investigation of the potential role of methyl benzoate in the detection of vapor from cocaine HCl generated under high humidity conditions. These studies were carried out using operant psychophysical testing methods in a laboratory setting. Odor stimuli were generated and delivered by vapor generation systems, the outputs from which were characterized by thermal desorption gas chromatography and mass spectrometry. Dogs were shown to be capable of detecting the vapor from an illicit sample of cocaine HCl at levels in which the concentration of methyl benzoate in that vapor was less than 0.1 parts per billion (ppb) in air. They were much less capable of detecting vapor from pharmaceutical cocaine presumably due to the reduced abundance of methyl benzoate as well as other vapor constituents in the pharmaceutical sample as compared to the abundance of such constituents in the illicit sample. Sensitivity to methyl benzoate (thresholds ranged between 5 and 25 ppb) was determined to be less than the methyl benzoate concentration present in detectable dilution levels of the vapor from cocaine HCl. In testing for the potential role of methyl benzoate in the detection of vapor from cocaine, the responding of only one dog showed a clear tendency to generalize across methyl benzoate and the vapor from cocaine. Methyl benzoate was assessed to be an important constituent of the vapor from cocaine, but, as not the only constituent of that vapor important in dogs' detection of cocaine HCl.
Kreeger, Terry John. THE PHYSIOLOGICAL, BIOCHEMICAL, AND PATHOLOGICAL RESPONSES OF WILD CANIDS TO STRESS (FOX, WOLF). Dissertation Abstracts International. Volume: 49-12, Section: B, page: 5174. Abstract The physiology and endocrine responses to stress in wild canids were examined. Captive red foxes (Vulpes vulpes) were caught under controlled conditions in padded, foot-hold traps. Data from these foxes were compared to both trapped and untrapped (control), free-ranging foxes. The heart rate and body temperature, measured by radiotelemetry, increased rapidly in trapped foxes ($P$ $<$ 0.05) but returned to pre-trapped values within 70 min of capture. Trapped foxes had elevated levels of adrenocorticotropin hormone (ACTH), beta-endorphin, cortisol, bilirubin, alkaline phosphatase, lactate dehydrogenase, and creatine kinase compared to controls ($P$ $<$ 0.05). Luteinizing hormone (LH) values were lower in trapped foxes ($P$ $<$ 0.04). Trapped foxes had increased leukocytes ($P$ $<$ 0.05) characterized by neutrophilia and lymphopenia. No limb lacerations, luxations, or fractures were noted in trapped foxes. Trapped foxes had higher incidences ($P$ $<$ 0.05) of congestion and acute hemorrhage in adrenal glands, heart, lung, kidney, and thyroid glands. These results were consistent with a diagnosis of acute stress and prolonged physical exertion in trapped foxes. The endocrine correlates of stress and reproduction were also examined in wolves (Canis lupus). Wolves injected with 50 IU ovine corticotropin releasing factor had significant ($P$ $<$ 0.02) elevations of ACTH and cortisol compared to saline-injected controls. Wolves injected with 25 IU ACTH or 2.2 mg/kg cortisol did not have altered baseline LH levels ($P$ $>$ 0.05). Luteinizing hormone levels were also unchanged in wolves pre-treated with 25 IU ACTH or 0.22 mg/kg dexamethasone, then given luteinizing hormone releasing hormone. These data indicate that acute elevations of pituitary-adrenocortical hormones do not alter LH secretion in wolves. However, 1.0 mg/kg of the opioid antagonist, naloxone, increased plasma LH levels while opioid agonist anesthesia decreased levels. These results indicated that the endogenous opioid system modulates LH release. Naloxone also depressed prolactin levels in intact and lactating wolves while not altering the prolactin release induced by thyrotropin releasing hormone. These data support an opioid control of prolactin release at the level of the hypothalamus. Neutered wolves given ACTH had significant ($P$ $<$ 0.0001) elevations of progesterone implicating the adrenal gland as a source of progesterone secretion in wolves.
Última atualização: 22/02/1998